SHR # 1127 :: The Trans-Generational Legacy Of DES PLUS How Safe Is Your Genetic Information On The Internet ::

Guest: Andrea Goldstein & Dr. Yaniv Erlich

The Daughters Of DES is a group keeping the information circulating about a synthetic estrogenic compound called Diethylstilbestrol used by doctors to treat women at risk of miscarriage from 1940 through the 1970's. It has serious transgenerational epigenetic effects that are still showing up in our population. It was also used in the raising of cattle and poultry for human consumption so even if you think you've avoided exposure... you may not have. Goldstein, a trained gynecological nurse and a women who was exposed to DES through her mother explains what to look for and what to do if you think you or someone you know was exposed. PLUS With more scientific studies being performed in the area of genetics, volunteers who are subjects in these studies are now learning that their personal genetic information and the genetic information of future descendants' privacy is at risk. A lack of security makes it so simple that anyone with a computer, Internet connection and asking the right questions can discover your genetic information!

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+1 # Hugh Easton 2013-02-04 16:51
DES had a second medical use besides prevention of miscarriage: chemically castrating men with prostate cancer. The dose required for chemical castration is 3mg per day; the starting dose for treatment of miscarriage was 5mg per day.

Testosterone plays a crucial role in driving male development, so what are the consequences likely to be if an unborn male child is exposed to high doses of a chemical castration agent for a large part of the pregnancy?

There's an untold side to the DES story: that of the DES sons. Among the ones I've been in contact with over the past year, there are four really common groups of problems:
* infertility
* intersex-relate d genital abnormalities including undescended testes, hypospadias and micropenis
* chronically low testosterone levels and other endocrine problems
*psychological problems, including ADHD and depression, and often gender identity problems too.
0 # cogrick2 2013-01-24 06:06
Here is the Facebook page. It's "DES Info".
+1 # Dr Jules Black FRCOG 2013-01-24 03:49
Did you know that DES was the first drug to be evaluated and cleared by the then fledgling FDA around 1938-9? Thus there has been enormous pressure on the FDA to deny responsibility for not having revealed the known effects on animals at the time, which should have prevented the drug being permitted in pregnancy. The US Govt. couldn't allow this new, authoritative Govt. body going down in flames.

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